National Football League
Aaron Rodgers and the Green Bay Packers attempt to maintain a hold of their NFC North division lead over Adrian Peterson and the Minnesota Vikings on "Sunday Night Football".
The Tampa Bay Buccaneers, who may be without star running back Doug Martin for the rest of the year, attempt to get their first win of the season against Cam Newton and the Carolina Panthers, who are looking to go above-.500 for the first time since 2008.
The New York Giants are looking for their first victory of the season, having started the season 0-6, and go up against the Minnesota Vikings, who will be starting free agent quarterback Josh Freeman after he was released by the Tampa Bay Buccaneers.
Peyton Manning returns, in a Denver Broncos uniform, to Indianapolis to face the Colts and Andrew Luck, in a week that saw his former employer take shots at his legacy with the organization.
The Seattle Seahawks try to extend their NFC West lead on "Thursday Night Football" as they travel to Arizona to take on the Cardinals, looking to keep pace with the division leader.
Philip Rivers and the San Diego Chargers, looking to get back to .500, will host Andrew Luck and the Indianapolis Colts, who are coming off a convincing victory over the previously undefeated Seattle Seahawks and taking control of the AFC South division.
The Dallas Cowboys' Tony Romo, trying to bounce back from last weeks shootout against Peyton Manning, will host Robert Griffin III, who are looking to cut down the Cowboy's and Philadelphia Eagles' NFC East lead. Also, former Super Bowl winners Drew Brees and Tom Brady go head-to-head in a late afternoon Week 6 match-up, as the New Orleans Saints take on the New England Patriots.
Also, Geno Smith and the New York Jets host the Pittsburgh Steelers and the undefeated Kansas City Chiefs square off against bitter division rival Oakland Raiders.
Jay Cutler and the Chicago Bears are looking to turn things around after losing their last two games at the expense of Eli Manning and the winless New York Giants on "Thursday Night Football".
After suffering back-to-back loses to the Miami Dolphins and New England Patriots, the Atlanta Falcons are looking to rebound at home against the rebuilding New York Jets on "Monday Night Football".
Also, Drew Brees and the undefeated New Orleans Saints go against the Chicago Bears tough defense, the 3-1 Detroit Lions look to extend their NFC Central division lead at the expense of Aaron Rodgers and the Green Bay Packers, and Andy Reid looks to guide the Kansas City Chiefs to a 5-0 start against the 3-1 Tennessee Titans.
The Cleveland Browns are 2-0 after their surprising trade of RB Trent Richardson, looking to extend their winning ways against rookie Buffalo Bills' QB EJ Manuel, who is coming off a Week 4 victory over the defending Super Bowl champion Baltimore Ravens.
Also, Robert Griffin III tries to snap Washington's 3-game losing streak against the Oakland Raiders, the Philadelphia Eagles must deal with Peyton Manning and the Denver Broncos' high-scoring offense, and the Seattle Seahawks attempt to stay undefeated against the Houston Texans.
The San Francisco 49ers, a favorite to reach the Super Bowl this year, have sputtered out of the gate and hope rebound against the St. Louis Rams, who hope to build on last year's success against the 49ers.
Peyton Manning and the 2-0 Denver Broncos high-powered offense travel to O.co Coliseum to take on long-time rival Oakland Raiders for a record 17th time on "Monday Night Football."