Daniel Bryan is set to face off against Randy Orton - their third match in eight days, in the main event. "The Viper" won their first "No Disqualification" match, last week on Raw, after WWE officials stopped the match when Bryan got injured. Bryan took the second match on Smackdown, but was dissatisfied with his count-out victory.
John Cena will address Mark Henry's "retirement" speech, in which "The World's Strongest Man" viciously attacked the WWE Champion before challenging Cena to a title match at the "Money In The Bank" pay-per-view.
Meanwhile, Vickie Guerrero has to navigate through the machinations of the McMahon Family after Triple H's edict that The Shield not interfere in Dean Ambrose's U.S. Title match against Kane last week, which was completely disregarded by the three-man wrecking crew. Will she side with Vince - who endorsed The Shield's way of doing "business" or will she side with Triple H - who may look to replace her as Raw Managing Supervisor?
Dolph Ziggler, still reeling from the lingering effects of the concussion that has kept him out of action, is looking to return to action as soon as possible. But will the beat down that the new World Heavyweight Champion, Alberto Del Rio, gave Ziggler last Friday on Smackdown slow down his progress?
CM Punk is expected to respond to Brock Lesnar's "message" - after getting laid out by "The Next Big Thing" during Punk's match against Del Rio, last week on Raw. Will Paul Heyman mediate this situation between his two clients or is Punk done as a "Heyman Guy"?